Medical Weight Loss That Works

Feel Better. Look Better. Live Better.

Lose weight with confidence

At Twelve28Rx, we offer medically guided weight loss solutions, including both injectable and oral treatments.

Start Your Journey Today

Why Choose Twelve28Rx

Proven Medical Treatments

Clinically backed GLP-1 therapies that target appetite, blood sugar, and metabolism for consistent, lasting weight loss.

Nationwide Access

Get expert care from the comfort of your home, no waiting rooms, no travel. We serve clients across the U.S. with licensed, state-compliant providers.

Tailored For You

Whether you’re just starting or hitting a plateau, our licensed providers design your treatment plan for your body and goals

Privacy + Convenience

Online visits, no waiting rooms, fast delivery. Your care, delivered to your door.

Top Weight Loss Solutions

Semaglutide (GLP-1 Injection)

A weekly injection that mimics GLP-1 to control appetite and improve blood sugar. Includes B12 to boost energy and weight management.

Starting at $348.30/month
3-month commitment • Total from $1,045

GLP-1/GIP (Tirzepatide)

Dual-action GLP-1/GIP for advanced weight loss and glucose balance. Glycine supports precise dosing and promotes metabolic wellness.

Starting at $516.60/month
3-month commitment – Total from $1,550

GLP-1 Sublingual Drops (Semaglutide)

Sublingual GLP-1 for appetite control and blood sugar support—no needles. Bypasses digestion for fast absorption; ideal for needle-averse users.

Starting at $348.30/month
3-month commitment – Total from $1,045

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1. Online Consultation

Complete a quick medical intake to get matched with a licensed provider.

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2. Personalized Treatment Plan

Our provider reviews your health history and prescribes a plan built for you.

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3. Fast, No-Contact Delivery

We ship your medications directly to your door in discreet packaging.

50% Off First Purchase

Care For Your Skin

Care For Yourself

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Hear From Our Clients

"I lost 22 pounds in just 3 months! The process was smooth, and the results blew me away. I feel confident again.”

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★★★★★

Emily G.
Happy Client

"I hit my goal weight after years of trying. Tirzepatide worked when nothing else did. Highly recommend Twelve28Rx.”

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★★★★★

Mark L.
Happy Client

“No needles? Yes please! The sublingual drops fit perfectly into my lifestyle. So easy.”


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★★★★★

Shannon D.
Happy Client

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Contact Us

Call us at: 844-GOT-1228

Mail us at: [email protected]