At Twelve28Rx, we offer medically guided weight loss solutions, including both injectable and oral treatments.


Clinically backed GLP-1 therapies that target appetite, blood sugar, and metabolism for consistent, lasting weight loss.

Get expert care from the comfort of your home, no waiting rooms, no travel. We serve clients across the U.S. with licensed, state-compliant providers.


Whether you’re just starting or hitting a plateau, our licensed providers design your treatment plan for your body and goals

Online visits, no waiting rooms, fast delivery. Your care, delivered to your door.


A weekly injection that mimics GLP-1 to control appetite and improve blood sugar. Includes B12 to boost energy and weight management.
Starting at $348.30/month
3-month commitment • Total from $1,045
Dual-action GLP-1/GIP for advanced weight loss and glucose balance. Glycine supports precise dosing and promotes metabolic wellness.
Starting at $516.60/month
3-month commitment – Total from $1,550



Sublingual GLP-1 for appetite control and blood sugar support—no needles. Bypasses digestion for fast absorption; ideal for needle-averse users.
Starting at $348.30/month
3-month commitment – Total from $1,045

Complete a quick medical intake to get matched with a licensed provider.


Our provider reviews your health history and prescribes a plan built for you.


We ship your medications directly to your door in discreet packaging.
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"I lost 22 pounds in just 3 months! The process was smooth, and the results blew me away. I feel confident again.”

★★★★★
Emily G.
Happy Client
"I hit my goal weight after years of trying. Tirzepatide worked when nothing else did. Highly recommend Twelve28Rx.”

★★★★★
Mark L.
Happy Client
“No needles? Yes please! The sublingual drops fit perfectly into my lifestyle. So easy.”

★★★★★
Shannon D.
Happy Client

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